Article

Cell cycle lengths of stem cells and their lineage from cellular demography

2020-11-20

Abstract excerpt

Adult stem cells and their transit-amplifying (TA) progeny dynamically alter their proliferation rates to maintain tissue homeostasis. To test how the division rates of stem cell and TA cells affect tissue growth and differentiation, we developed a computation strategy which estimates the average cell cycle lengths/lifespans of germline stem cells (GSCs) and their TA progeny from cellular demography. Analysis of t...

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Literature Corpus work: 96c48d93-82fe-541b-8298-1f761c066af8
DOI: 10.1101/2020.11.18.388314

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