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Article

Age-related Deterioration of Hematopoietic Stem Cells

30 Nov 2008

Abstract excerpt

Aging is the process of system deterioration over time in the whole body. Stem cells are self-renewing and therefore have been considered exempt from the aging process. Earlier studies by Hayflick showed that there is an intrinsic limit to the number of divisions that mammalian somatic cells can undergo, and cycling kinetics and ontogeny-related studies strongly suggest that even the most primitive stem cell...

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PMID: 24855509
DOI: 10.15283/ijsc.2008.1.1.55

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