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Conformational Dynamics of Na <sup>+</sup> -Pumping NADH-Quinone Oxidoreductase during Na <sup>+</sup> Translocation from AlphaFold-Facilitated Markov State Modeling

2026-02-01

Abstract excerpt

<h4>ABSTRACT</h4> The Na + -pumping NADH–quinone oxidoreductase (Na + -NQR) is a respiratory chain enzyme found in pathogenic bacteria, including Vibrio cholerae , and is essential for energy metabolism by generating a transmembrane Na + gradient that drives ATP synthesis and flagellar motility. Because the molecular structure of Na + -NQR is unrelated to the corresponding mitochondrial H⁺-pumping NADH-quino...

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Literature Corpus work
a40b6711-cf07-5a6f-bf41-d88089ffeac0
DOI
10.64898/2026.01.28.702413
Open publication

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Conformational Dynamics of Na <sup>+</sup> -Pumping NADH-Quinone Oxidoreductase during Na <sup>+</sup> Translocation from AlphaFold-Facilitated Markov State ModelingDOI 10.64898/2026.01.28.702413
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