Article

The intrinsically disordered N-terminus of the voltage-dependent anion channel

2020-09-25

Abstract excerpt

The voltage-dependent anion channel (VDAC) is a critical β-barrel membrane protein of the mitochondrial outer membrane, which regulates the transport of ions and ATP between mitochondria and the cytoplasm. In addition, VDAC plays a central role in the control of apoptosis and is therefore of great interest in both cancer and neurodegenerative diseases. Although not fully understood, it is presumed that the gating...

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Literature Corpus work: 4b03b5a8-c648-55f0-bf05-16a8dbe5e2d3
DOI: 10.1101/2020.09.24.311332

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