Article

VERY EARLY REMISSION AND INCREASED APOPTOSIS WITH THE USE OF PENTOXIFYLLINE IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA

2020-11-16

Abstract excerpt

<h4>Background: </h4> Acute lymphoblastic leukemia (ALL) is the most common cancer in childhood, and despite advances in cancer treatment, there are still cases of relapse and death secondary to resistance to chemotherapy or apoptosis. One of the mechanisms is the activation of the IKK/NF-κB signaling pathway that leads to the expression of genes that interfere with apoptosis. Pentoxifylline (PTX) can block phosph...

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Literature Corpus work: a3d325bc-1bce-5d67-b33c-6e8fcde97b78
DOI: 10.22541/au.160553055.56047064/v1

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