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Article

Low spontaneous apoptosis index at diagnosis predicts a high-risk phenotype in paediatric acute lymphoblastic leukaemia.

The Indian journal of medical research - 1 Mar 2018

Singh Ankita, Bhatia Prateek, Trehan Amita, Bansal Deepak, Singh Ajit, Bhatia Alka

Abstract excerpt

Background & objectives: Significance of apoptosis as a prognostic marker is less well studied in paediatric acute lymphoblastic leukaemia (ALL) cases. Hence, a prospective study, involving 30 paediatric ALL cases, was done to assess the clinical relevance of in vivo apoptosis. Methods: Peripheral blood mononuclear cells from all patients were subjected to annexin V/propidium iodide staining to detect the degree...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

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Identifiers

PMID: 29923513
DOI: 10.4103/ijmr.IJMR_303_16
PMCID: PMC6022376

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