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Article

Comparative measurement of spontaneous apoptosis in pediatric acute leukemia by different techniques

21 Oct 2003

Abstract excerpt

BACKGROUND: To distinguish between subgroups of patients with acute leukemia, the rate of spontaneous (culture-induced) apoptosis of leukemic cells was evaluated using five methods. METHODS: Leukemic cells (cells) from the bone marrow of children with acute lymphoblastic leukemia (ALL, n = 112) and acute myeloid leukemia (AML, n = 30) were cultured for 20 h in vitro. The level of apoptosis was detected by...

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PMID: 14582133
DOI: 10.1002/cyto.b.10056

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