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Revisiting the effect of pharmaceuticals on transmission stage formation in the malaria parasite <i>Plasmodium falciparum</i>

2021-11-19

Abstract excerpt

Malaria parasites rely on specialized stages, called gametocytes, to ensure human-to-human transmission. The formation of these sexual precursor cells is initiated by commitment of blood stage parasites to the sexual differentiation pathway. Plasmodium falciparum , the most virulent of six parasite species infecting humans, employs nutrient sensing to control the rate at which sexual commitment is initiated, and...

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Literature Corpus work
c147991a-57f8-5612-968a-fe7826a93529
DOI
10.1101/2021.11.18.469097
Open publication

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