Article

Discovery and functional interrogation of SARS-CoV-2 protein-RNA interactions

2022-02-24

Abstract excerpt

The COVID-19 pandemic is caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). The betacoronvirus has a positive sense RNA genome which encodes for several RNA binding proteins. Here, we use enhanced crosslinking and immunoprecipitation to investigate SARS-CoV-2 protein interactions with viral and host RNAs in authentic virus-infected cells. SARS-CoV-2 proteins, NSP8, NSP12, and nucleocapsid disp...

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Literature Corpus work: a3a91832-ea18-5b0c-ab35-014e287d552f
DOI: 10.1101/2022.02.21.481223

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