Article

Systematic discovery and functional interrogation of SARS-CoV-2 viral RNA-host protein interactions during infection

2020-10-06

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a pandemic with growing global mortality. There is an urgent need to understand the molecular pathways required for host infection and anti-viral immunity. Using comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS), we identified 309 host proteins that bind the SARS-CoV-2 RNA during active infection. Integr...

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Literature Corpus work: 093d9e41-cefb-5cc8-b7e8-183109e0aed3
DOI: 10.1101/2020.10.06.327445

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