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The SARS-CoV-2 RNA–protein interactome in infected human cells

21 Dec 2020

Abstract excerpt

Characterizing the interactions that SARS-CoV-2 viral RNAs make with host cell proteins during infection can improve our understanding of viral RNA functions and the host innate immune response. Using RNA antisense purification and mass spectrometry, we identified up to 104 human proteins that directly and specifically bind to SARS-CoV-2 RNAs in infected human cells. We integrated the SARS-CoV-2 RNA interactome...

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PMID: 33349665
DOI: 10.1038/s41564-020-00846-z

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