Article

Redefining tissue specificity of genetic regulation of gene expression in the presence of allelic heterogeneity

2021-07-01

Abstract excerpt

Understanding the mechanisms that underlie genetic regulation of gene expression is crucial to explaining the diversity that governs complex traits. Large scale expression quantitative trait locus (eQTL) studies have been instrumental in identifying genetic variants that influence the expression of target genes. However, a large fraction of disease-associated genetic variants have not been clearly explained by cur...

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Literature Corpus work: 3ebb3993-8509-5c93-a5f1-6df2d7588078
DOI: 10.1101/2021.06.28.21259545

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