Article

Mechanisms of tissue-specific genetic regulation revealed by latent factors across eQTLs

2019-10-06

Abstract excerpt

<h4>Background</h4> Genetic regulation of gene expression, revealed by expression quantitative trait loci (eQTLs), varies across tissues in complex patterns ranging from highly tissue-specific effects to effects shared across many or all tissues. Improved characterization of these patterns may allow us to better understand the biological mechanisms that underlie tissue-specific gene regulation and disease etiolog...

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Literature Corpus work: fec63692-f34e-5134-b3fa-c679f7d06cad
DOI: 10.1101/785584

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