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Combined therapy with pirfenidone and nintedanib counteracts fibrotic silicosis in mice

2023-10-20

Abstract excerpt

Abstract Background and Purpose Pneumoconiosis, especially silicosis has emerged as a prominent occupational disease with remarkable global implications with no definitive cure available. While pirfenidone and nintedanib have been approved in treating idiopathic pulmonary fibrosis, their potential efficacy as anti-fibrotic agents in advanced silicosis warrants further investigation. Thus, we aimed to assess the in...

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Literature Corpus work
2e3d3d84-861e-55db-91bc-c70082ef6202
DOI
10.22541/au.169779616.60916387/v1
Open publication

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Combined therapy with pirfenidone and nintedanib counteracts fibrotic silicosis in miceDOI 10.22541/au.169779616.60916387/v1
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