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Article

Biotin rescues manganese-induced Parkinson’s disease phenotypes and neurotoxicity

2023-11-21

Abstract excerpt

Occupational exposure to manganese (Mn) induces manganism and has been widely linked as a contributing environmental factor to Parkinson’s disease (PD), featuring dramatic signature overlaps between the two in motor symptoms and clinical hallmarks. However, the molecular mechanism underlying such link remains elusive, and for combating PD, effective mechanism-based therapies are lacking. Here, we developed an adul...

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Literature Corpus work
a336be5c-70a5-5c12-8d31-887a9c4450c0
DOI
10.1101/2023.11.21.568033
Open publication

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Biotin rescues manganese-induced Parkinson’s disease phenotypes and neurotoxicityDOI 10.1101/2023.11.21.568033
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