Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Coronavirus Replication Complex Formation Utilizes Components of Cellular Autophagy

1 Mar 2004

Abstract excerpt

The coronavirus mouse hepatitis virus (MHV) performs RNA replication on double membrane vesicles (DMVs) in the cytoplasm of the host cell. However, the mechanism by which these DMVs form has not been determined. Using genetic, biochemical, and cell imaging approaches, the role of autophagy in DMV formation and MHV replication was investigated. The results demonstrated that replication complexes co-localize with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to CRISPR and Genetic Engineering

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 14699140
DOI: 10.1074/jbc.m306124200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Coronavirus Replication Complex Formation Utilizes Components of Cellular AutophagyPMID 14699140Read ↗

Japanese encephalitis virus replication is negatively regulated by autophagy and occurs on LC3-I- and EDEM1-containing membranesSemantic proximity Read ↗

Contribution of autophagy machinery factors to HCV and SARS-CoV-2 replication organelle formationSemantic proximity Read ↗

Convergent use of phosphatidic acid for Hepatitis C virus and SARS-CoV-2 replication organelle formationSemantic proximity Read ↗

TRIM proteins: New players in virus-induced autophagySemantic proximity Read ↗

Autophagy promotes the replication of encephalomyocarditis virus in host cellsSemantic proximity Read ↗

Autophagy and RNA virus interactomes reveal IRGM as a common targetSemantic proximity Read ↗

Astrovirus replication is dependent on induction of double-membrane vesicles through a PI3K-dependent, LC3-independent pathwaySemantic proximity Read ↗

Impact of the Autophagy Machinery on Hepatitis C Virus InfectionSemantic proximity Read ↗

The autophagy elongation complex (ATG5-12/16L1) positively regulates HCV replication and is required for wild-type membranous web formation.Semantic proximity Read ↗

Hepatitis C virus and autophagySemantic proximity Read ↗

Virus-Induced Cytoplasmic Aggregates and Inclusions Are Critical Cellular Regulatory and Antiviral FactorsSemantic proximity Read ↗

Autophagy in HCV Replication and Protein TraffickingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.