Article

Effect of siRNA-promoted Silencing of Prion Protein on Doxorubicin-induced Cell Death Machineries in Human Adriamycin-resistant Small Cell Lung Cancer Cell Line H69AR

2023-06-26

Abstract excerpt

<title>Abstract</title> <p>Background Multidrug resistance is one of major challenges in cancer therapy. Recent data have proposed that among its many cellular functions, prion protein (PrP) is also involved in the acquisition of a multidrug resistance phenotype of cancer cells. In this study, we examined the effect of PrP on doxorubicin-induced cell death in the human adriamycin-resistant small cell lung cancer...

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Literature Corpus work: a3344a9c-8101-53a8-9453-24058f060e89
DOI: 10.21203/rs.3.rs-3052321/v1

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