Article
Overexpression and significance of prion protein in gastric cancer and multidrug-resistant gastric carcinoma cell line SGC7901/ADR.
International journal of cancer - 10 Jan 2005
Du Jingping, Pan Yanglin, Shi Yongquan, Guo Changcun, Jin Xiaohang, Sun Li, Liu Na, Qiao Taidong, Fan Daiming
Abstract excerpt
In our previous work, cellular prion protein (PrPc) was identified as an upregulated gene in adriamycin-resistant gastric carcinoma cell line SGC7901/ADR compared to its parental cell line SGC7901. Here we investigate the expression of PrPc in gastric cancer and whether it was involved in multidrug resistance (MDR) of gastric cancer. We demonstrated that PrPc was ubiquitously expressed in gastric cancer cell...
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