Article

Sofosbuvir protects human brain organoids against SARS-CoV-2

2020-05-31

Abstract excerpt

COVID-19 was rapidly declared a pandemic by the World Health Organization, only three months after the initial outbreak in Wuhan, China. Early clinical care mainly focused on respiratory illnesses. However, a variety of neurological manifestations in both adults and newborns are also emerging. To determine whether SARS-CoV-2 could target the human brain, we infected iPSC-derived human brain organoids. Our findings...

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Literature Corpus work: a329f020-6931-5f92-b2e4-dd0e26ea8834
DOI: 10.1101/2020.05.30.125856

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