Article

Gamma secretase inhibitors inhibit ovarian cancer development and enhance olaparib’s anti-ovarian cancer activity and its mechanism

2020-05-19

Abstract excerpt

<h4>Background</h4> Ovarian cancer is the fifth leading cause of cancer-related deaths in women. Although cytoreductive surgery combined with chemotherapy and / or targeted therapy has achieved a certain effect, but advanced patients have limited clinical benefits and are prone to relapse. Among them, Notch / jagged1 and Wnt / β-catenin signal transduction plays an important role in the development of ovarian can...

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Literature Corpus work: a3226d6a-e535-5c6a-a262-0c609964abf0
DOI: 10.1101/2020.05.19.103853

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