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Article

PINK1-PTEN axis promotes metastasis and chemoresistance in ovarian cancer via non-canonical pathway

9 Nov 2023

Abstract excerpt

BACKGROUND: Ovarian cancer is commonly associated with a poor prognosis due to metastasis and chemoresistance. PINK1 (PTEN-induced kinase 1) is a serine/threonine kinase that plays a crucial part in regulating various physiological and pathophysiological processes in cancer cells. METHODS: The ATdb database and "CuratedOvarianData" were used to evaluate the effect of kinases on ovarian cancer survival. The gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37940999
DOI: 10.1186/s13046-023-02823-w

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