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Dissecting the cell of origin of aberrant SALL4 expression in myelodysplastic syndrome

2022-12-05

Abstract excerpt

Myelodysplastic syndrome (MDS) is a group of heterogeneous diseases characterized by cytologic dysplasia and cytopenias resulting from ineffective hematopoiesis. Oncofetal protein SALL4 is a known oncogene in MDS and its baseline expression level serves as a prognostic biomarker for MDS at the time of diagnosis. In addition, a recent study showed that SALL4 upregulation following hypomethylating agent treatment in...

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Literature Corpus work
a3141743-5031-5e47-9950-21126b77de92
DOI
10.1101/2022.12.05.518121
Open publication

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Dissecting the cell of origin of aberrant SALL4 expression in myelodysplastic syndromeDOI 10.1101/2022.12.05.518121
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