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Immunophenotypic, cytogenetic, and mutational characterization of cell lines derived from myelodysplastic syndrome patients after progression to acute myeloid leukemia.

Genes, chromosomes & cancer - 1 Mar 2017

Palau Anna, Mallo Mar, Palomo Laura, Rodríguez-Hernández Ines, Diesch Jeannine, Campos Diana, Granada Isabel, Juncà Jordi, Drexler Hans G, Solé Francesc, Buschbeck Marcus

Abstract excerpt

Leukemia cell lines have been widely used in the hematology field to unravel mechanistic insights and to test new therapeutic strategies. Myelodysplastic syndromes (MDS) comprise a heterogeneous group of diseases that are characterized by ineffective hematopoiesis and frequent progress to acute myeloid leukemia (AML). A few cell lines have been established from MDS patients after progression to AML but their...

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Identifiers

PMID: 27750403
DOI: 10.1002/gcc.22430

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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