Article
Profiling myelodysplastic syndromes by mass cytometry demonstrates abnormal progenitor cell phenotype and differentiation.
Cytometry. Part B, Clinical cytometry - 1 Mar 2020
Behbehani Gregory K, Finck Rachel, Samusik Nikolay, Sridhar Kunju, Fantl Wendy J, Greenberg Peter L, Nolan Garry P
Abstract excerpt
BACKGROUND: We sought to enhance the cytometric analysis of myelodysplastic syndromes (MDS) by performing a pilot study of a single cell mass cytometry (MCM) assay to more comprehensively analyze patterns of surface marker expression in patients with MDS. METHODS: Twenty-three MDS and five healthy donor bone marrow samples were studied using a 34-parameter mass cytometry panel utilizing barcoding and internal...
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