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A 4-gene leukemic stem cell score can independently predict the prognosis of myelodysplastic syndrome patients

20 Feb 2020

Abstract excerpt

Myelodysplastic syndrome (MDS) comprised a heterogeneous group of diseases. The prognosis of patients varies even in the same risk groups. Searching for novel prognostic markers is warranted. Leukemic stem cells (LSCs) are responsible for chemoresistance and relapse in leukemia. Recently, expressions of 17 genes related to stemness of LSCs were found to be associated with prognosis in acute myeloid leukemia...

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Acute Myeloid Leukemia Research
Epigenetics and DNA Methylation
Histone Deacetylase Inhibitors Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32078680
DOI: 10.1182/bloodadvances.2019001185

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