Article

Generating fast-twitch myotubes <i>in vitro</i> using an optogenetic-based, quantitative contractility assay

2022-10-05

Abstract excerpt

The composition of fiber types within skeletal muscle impacts the tissue’s physiological characteristics and susceptibility to disease and ageing. In vitro systems should therefore account for fiber type composition when modelling muscle conditions. To induce fiber specification in vitro , we designed a quantitative contractility assay based on optogenetics and particle image velocimetry. We submitted cultured m...

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Literature Corpus work: a30daca6-e634-5c6a-b2a7-975552a3f62f
DOI: 10.1101/2022.10.04.510824

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