Article
MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo.
Circulation research - 2 Feb 2018
Sala Luca, van Meer Berend J, Tertoolen Leon G J, Bakkers Jeroen, Bellin Milena, Davis Richard P, Denning Chris, Dieben Michel A E, Eschenhagen Thomas, Giacomelli Elisa, Grandela Catarina, Hansen Arne, Holman Eduard R, Jongbloed Monique R M, Kamel Sarah M, Koopman Charlotte D, Lachaud Quentin, Mannhardt Ingra, Mol Mervyn P H, Mosqueira Diogo, Orlova Valeria V, Passier Robert, Ribeiro Marcelo C, Saleem Umber, Smith Godfrey L, Burton Francis L, Mummery Christine L
Abstract excerpt
RATIONALE: There are several methods to measure cardiomyocyte and muscle contraction, but these require customized hardware, expensive apparatus, and advanced informatics or can only be used in single experimental models. Consequently, data and techniques have been difficult to reproduce across models and laboratories, analysis is time consuming, and only specialist researchers can quantify data. OBJECTIVE: Here,...
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