Article

Systemic coagulopathy drives host lethality in a new Drosophila tumor model

2022-05-11

Abstract excerpt

<h4>ABSTRACT</h4> Malignant tumors trigger a complex network of inflammatory and wound repair responses, prompting Dvorak’s characterization of tumors as ‘wounds that never heal’ 1 . Some of these responses lead to profound defects in blood clotting, such as Disseminated Intravascular Coagulopathy (DIC), which correlate with poor prognoses 2–4 . Here, we demonstrate that a new tumor model in Drosophila provoke...

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Literature Corpus work: a3078226-b26b-5cdf-98bf-4dd32570e28a
DOI: 10.1101/2022.05.11.491522

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