Article
Multiple strategies of oxygen supply in Drosophila malignancies identify tracheogenesis as a novel cancer hallmark.
Scientific reports - 12 Mar 2015
Grifoni Daniela, Sollazzo Manuela, Fontana Elisabetta, Froldi Francesca, Pession Annalisa
Abstract excerpt
Angiogenesis is the term used to describe all the alterations in blood vessel growth induced by a tumour mass following hypoxic stress. The occurrence of multiple strategies of vessel recruitment favours drug resistance, greatly complicating the treatment of certain tumours. In Drosophila, oxygen is conveyed to the internal organs by the tracheal system, a closed tubular network whose role in cancer growth is so...
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