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Article

Causal association between plasma metabolites and diverse autoimmune diseases: a two-sample bidirectional mendelian randomization study.

Frontiers in immunology - 1 Jan 2024

Yuan Xiwen, Yang Peiyan, Hu Jiapeng, Cai Dixin, Hu Baoshan, Rui Gang, Lin Zhiming

Abstract excerpt

Background: Autoimmune diseases (ADs) are a category of conditions characterized by misrecognition of autologous tissues and organs by the immune system, leading to severe impairment of patients' health and quality of life. Increasing evidence suggests a connection between fluctuations in plasma metabolites and ADs. However, the existence of a causal relationship behind these associations remains uncertain....

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Identifiers

PMID: 39575250
DOI: 10.3389/fimmu.2024.1437688
PMCID: PMC11578997

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