Article
Naturally occurring tolerance acquisition to foods in previously allergic children is characterized by antigen specificity and associated with increased subsets of regulatory T cells.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Nov 2015
Qamar N, Fishbein A B, Erickson K A, Cai M, Szychlinski C, Bryce P J, Schleimer R P, Fuleihan R L, Singh A M
Abstract excerpt
BACKGROUND: Food allergy affects approximately 6-8% of children, and increasing in prevalence. Some children naturally outgrow their food allergy without intervention, but the mechanisms by which this occurs remain poorly understood. We sought to investigate the role of regulatory T cells in the development of naturally acquired tolerance. METHODS: Fifty-eight children (1-18 years) with either egg or peanut...
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