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Article

Current Strategies to Modulate Regulatory T Cell Activity in Allergic Inflammation

26 May 2022

Abstract excerpt

Over the past decades, atopic diseases, including allergic rhinitis, asthma, atopic dermatitis, and food allergy, increased strongly worldwide, reaching up to 50% in industrialized countries. These diseases are characterized by a dominating type 2 immune response and reduced numbers of allergen-specific regulatory T (Treg) cells. Conventional allergen-specific immunotherapy is able to tip the balance towards...

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PMID: 35720406
DOI: 10.3389/fimmu.2022.912529

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