Article

Loss of miR-16-1-3p Activity Predicts Chemoresistance and Progression in Osteosarcoma: An Integrative Clinicopathologic Study

2025-11-13

Abstract excerpt

<title>Abstract</title> Introduction Chemotherapy resistance contributes significantly to mortality in osteosarcoma (OS) patients. The role of miR-16, miR-16-1-3p, and miR-16-2-3p in modulating chemotherapy response and disease progression in OS remains unclear. Methods RNA-seq and clinical data from 82 OS patients in the TARGET-OS database were analyzed. Patients were classified by progression status (progres...

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Literature Corpus work: a2cd8c12-6c65-5a2b-a3fe-6b4b822d60b4
DOI: 10.21203/rs.3.rs-7665473/v1

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