Article

MicroRNA-mRNA networks define translatable molecular outcome phenotypes in osteosarcoma

2019-10-03

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> There is a lack of well validated biomarkers in osteosarcoma, a rare, recalcitrant disease with variable outcome and poorly understood biologic behavior, for which treatment standards have stalled for decades. The only standard prognostic factor in osteosarcoma remains the amount of pathologic necrosis following pre-operative chemotherapy, which does not adequately capture the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9316a737-d196-57a2-b59a-a0e7f577c3c3
DOI: 10.1101/19007740

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

MicroRNA-mRNA networks define translatable molecular outcome phenotypes in osteosarcomaDOI 10.1101/19007740Read

MicroRNA-mRNA networks define translatable molecular outcome phenotypes in osteosarcoma.Semantic proximity Read

MicroRNA paraffin-based studies in osteosarcoma reveal reproducible independent prognostic profiles at 14q32Semantic proximity Read

A dynamic microRNA profile that tracks a chemotherapy resistance phenotype in osteosarcoma. Implications for novel therapeuticsSemantic proximity Read

Construction of a Survival Prediction Model and Molecular Subtype Analysis Based on TARGET Osteosarcoma Multi-omics DataSemantic proximity Read

Single-cell RNA landscape of the intratumoral heterogeneity and expression of angiogenesis-related genes in osteosarcomaSemantic proximity Read

Molecular characterization of metastatic osteosarcoma: Differentially expressed genes, transcription factors and microRNAsSemantic proximity Read

Comprehensive analysis of potential cellular communication networks in advanced osteosarcoma using single-cell RNA sequencing dataSemantic proximity Read

Single-cell RNA sequencing reveals osteosarcoma microenvironment differences between chemotherapy and without chemotherapySemantic proximity Read

Prognostic value of microRNAs in osteosarcoma: A meta-analysis.Semantic proximity Read

Osteosarcoma Multi-omics Landscape and SubtypesSemantic proximity Read

Single-cell RNA sequencing reveals the communications between tumor microenvironment components and tumor metastasis in osteosarcomaSemantic proximity Read

Identification of critical genes associated with human osteosarcoma metastasis based on integrated gene expression profilingSemantic proximity Read