Article

MiR-16-1 <sup></sup> and miR-16-2 <sup></sup> possess strong tumor suppressive and anti-metastatic properties in osteosarcoma

2018-09-09

Abstract excerpt

Osteosarcoma (OS) is an aggressive malignancy affecting mostly children and adolescents. MicroRNAs (miRNAs) play important roles in OS development and progression. Here we found that miR-16-1* and miR-16-2* “passenger” strands as well as the “lead” miR-16 strand possess strong tumor suppressive functions in human OS. We report different although strongly overlapping functions for miR-16-1* and miR-16-2* in OS cell...

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Literature Corpus work: 8a29fff3-dc95-5189-8cdf-66a8200af96e
DOI: 10.1101/412411

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