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Article

Mitochondrial remodeling in colorectal cancer initiation, progression, metastasis, and therapy: A review

8 May 2023

Abstract excerpt

Colorectal cancer (CRC) is a major health concern with multifactorial pathophysiology representing intense therapeutic challenges. It is well known that deregulation of spatiotemporally-controlled signaling pathways and their metabolic reprogramming effects play a pivotal role in the development and progression of CRC. As such, the mitochondrial role in CRC initiation gained a lot of attention recently, as it is...

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PMID: 37182313
DOI: 10.1016/j.prp.2023.154509

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