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Contrasting autoimmune and treatment effects reveals baseline set points of immune toxicity following checkpoint inhibitor treatment

2022-06-06

Abstract excerpt

Immune checkpoint inhibitors (ICIs) have changed the cancer treatment landscape, but severe immune-related adverse events (irAEs) can be life-threatening or fatal and may prohibit patients from receiving further ICI treatment. While the clinical features of irAEs are well documented, molecular signatures, predictive biomarkers, and mechanisms of impending irAEs are largely unknown. In addition, the markers and mec...

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Literature Corpus work
a26a1f74-fa9d-5144-abf0-04e2946e7f08
DOI
10.1101/2022.06.05.494592
Open publication

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Contrasting autoimmune and treatment effects reveals baseline set points of immune toxicity following checkpoint inhibitor treatmentDOI 10.1101/2022.06.05.494592
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