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Article

Bridging clinical phenotypes with molecular mechanisms in autoimmune irAEs: An Etiopathogenic framework.

Best practice & research. Clinical rheumatology - 1 Mar 2026

Elg-Salsman Whitney

Abstract excerpt

Immune checkpoint inhibitors (ICI) have transformed the field of oncology and can induce a durable cancer treatment response in select cancer patients. ICI binding to these checkpoints allows the immune system to be activated in order to target tumor death, but this activation also brings multiple off-target side effects called immune related adverse events (irAE's) including rheumatic irAE's. Review aims will...

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Identifiers

PMID: 42115015
DOI: 10.1016/j.berh.2026.102152

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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