Article

Cell aggregation prevents anoikis and induces CD44 cleavage by maintaining lipid raft integrity to promote triple negative breast cancer metastasis

2023-02-14

Abstract excerpt

<title>Abstract</title> <p>Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype, and metastasis is the major cause of cancer morbidity and mortality. Therefore, it is urgent to discover novel therapeutic targets and develop effective treatments for this lethal disease. Circulating tumor cells (CTCs) are considered “seeds of metastasis”. Compared to single CTCs, our previous studies ha...

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Literature Corpus work: a241af62-1585-583a-b33c-e1d86aba378c
DOI: 10.21203/rs.3.rs-2535728/v1

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