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Article

Platelet PI3Kβ regulates breast cancer metastasis

2024-09-14

Abstract excerpt

Platelets promote tumor metastasis by several mechanisms. Platelet-tumor cell interactions induce the release of platelet cytokines, chemokines, and other factors that promote tumor cell epithelial-mesenchymal transition and invasion, granulocyte recruitment to circulating tumor cells (CTCs), and adhesion of CTCs to the endothelium, assisting in their extravasation at metastatic sites. Previous studies have shown...

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Identifiers and source

Literature Corpus work
900cc767-2fd6-58e4-ba7b-872c312c34bf
DOI
10.1101/2024.09.10.612261
Open publication

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Platelet PI3Kβ regulates breast cancer metastasisDOI 10.1101/2024.09.10.612261
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