Article

STING agonist-mediated endothelial cell activation drives NK cells and neutrophils-dependent pulmonary inflammation

2026-03-12

Abstract excerpt

Stimulator of interferon genes (STING) agonists and derivative molecules have been extensively developed for tumor immunotherapy. However, systemic exposure toxicity risks have constrained clinical trial progression and even threatened patient lives. Currently, systematic toxicity assessments for STING agonists remain lacking, with the mode of action for major organ injury yet to be elucidated. Here, we focused on...

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Literature Corpus work: a236cd90-4df8-5a85-8250-ead5eaa8395a
DOI: 10.64898/2026.03.10.710764

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