Article

Circulatory proteins shape microglia state and boost phagocytosis

2024-10-02

Abstract excerpt

<h4>Summary</h4> Microglia, the brain’s immune cells, are highly responsive to their local environment. Given that circulatory proteins can enter the brain, we asked whether microglia are responsive to such proteins. Here, we identify a stable population of microglia specialized to take up circulatory proteins in a region-specific manner under physiological conditions; human hematopoietic stem cell-derived microg...

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Literature Corpus work: a21cf9fc-12e1-5d19-a0b7-b824822c9418
DOI: 10.1101/2024.09.30.615861

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