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Article

Brain perivascular macrophages: characterization and functional roles in health and disease.

Journal of molecular medicine (Berlin, Germany) - 1 Nov 2017

Faraco Giuseppe, Park Laibaik, Anrather Josef, Iadecola Costantino

Abstract excerpt

Perivascular macrophages (PVM) are a distinct population of resident brain macrophages characterized by a close association with the cerebral vasculature. PVM migrate from the yolk sac into the brain early in development and, like microglia, are likely to be a self-renewing cell population that, in the normal state, is not replenished by circulating monocytes. Increasing evidence implicates PVM in several disease...

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Identifiers

PMID: 28782084
DOI: 10.1007/s00109-017-1573-x
PMCID: PMC5812456

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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