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Acute Exposure of Upcyte® Hepatocytes to Sub-lethal Concentrations of Graphene Oxide: Impairment of Phase-I Xenobiotic Metabolism and Albumin Transcription

2021-01-18

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>Graphene Oxide (GO) is a promising candidate for nanomedicine applications. Due to the central role of liver in biotransformation of xenobiotics and drugs, the impact of GO on hepatic functional cells represents a crucial evaluation step for its potential implementation as drug. Primary human hepatocytes (PHH) are the election model for studying drug toxicity and...

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Literature Corpus work
a1e760ac-f97c-55b9-b273-a862ad5ade6c
DOI
10.21203/rs.3.rs-147026/v1
Open publication

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Acute Exposure of Upcyte® Hepatocytes to Sub-lethal Concentrations of Graphene Oxide: Impairment of Phase-I Xenobiotic Metabolism and Albumin TranscriptionDOI 10.21203/rs.3.rs-147026/v1
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