Article

From Flies to Humans: A Conserved Role of CEBPZ, NOC2L, and NOC3L in rRNA Processing and Tumorigenesis

2025-01-14

Abstract excerpt

NOC1, NOC2, and NOC3 are evolutionarily conserved nucleolar proteins that play an essential role in the maturation and processing of ribosomal RNA (rRNA). NOC1, in Drosophila is necessary to sustain rRNA processing, whereas its depletion leads to impaired polysome formation, reduced protein synthesis, and induces apoptosis. In this study, we demonstrated that the RNA-regulatory functions of NOC1 are conserved in...

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Literature Corpus work: a1d1c5cd-a2b0-5c2d-aacc-b8be5627dba0
DOI: 10.1101/2025.01.11.632529

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From Flies to Humans: A Conserved Role of CEBPZ, NOC2L, and NOC3L in rRNA Processing and TumorigenesisDOI 10.1101/2025.01.11.632529Read

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