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The Clinical Features and Prognosis of NPM1/FLT3-ITD/DNMT3A Triple-mutated Acute Myeloid Leukaemia

2021-11-22

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<title>Abstract</title> <p><bold>Purpose: </bold>Previous studies have shown that patients with NPM1+/FLT3-ITD+ acute myeloid leukaemia (AML) have a poor prognosis, especially those with a high FLT3-ITD allelic ratio. However, no studies have confirmed a clear prognostic impact of DNMT3A on NPM1+/FLT3-ITD+ AML patients. <bold>Methods:</bold> Our study included a total of 165 patients with newly diagnosed non-acut...

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Literature Corpus work: a1a9f27b-dd1a-549f-9cf0-04ee2b1e3a48
DOI: 10.21203/rs.3.rs-1063695/v1

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