Article

Neighboring macrophage-induced alteration in the phenotype of colorectal cancer cells in the tumor budding area

2023-08-16

Abstract excerpt

<h4>Background: </h4> A higher number of tumor buds in the invasive front of colorectal cancer (CRC) specimens has been shown to contribute to a poor prognosis in CRC patients. Because macrophages (Mφs) have been demonstrated to alter the phenotype of cancer cells, we hypothesized that the phenotype of CRC cells in the tumor budding (TB) area might be changed by the interaction between CRC cells and Mφs. Methods...

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Literature Corpus work: 9b806cce-025c-5eaf-8788-adffc2cf72ed
DOI: 10.21203/rs.3.rs-3248056/v1

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