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Article

RGC32 induces epithelial-mesenchymal transition by activating the Smad/Sip1 signaling pathway in CRC.

Scientific reports - 4 May 2017

Wang Xiao-Yan, Li Sheng-Nan, Zhu Hui-Fang, Hu Zhi-Yan, Zhong Yan, Gu Chuan-Sha, Chen Shi-You, Liu Teng-Fei, Li Zu-Guo

Abstract excerpt

Response gene to complement 32 (RGC32) is a transcription factor that regulates the expression of multiple genes involved in cell growth, viability and tissue-specific differentiation. However, the role of RGC32 in tumorigenesis and tumor progression in colorectal cancer (CRC) has not been fully elucidated. Here, we showed that the expression of RGC32 was significantly up-regulated in human CRC tissues versus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28470188
DOI: 10.1038/srep46078
PMCID: PMC5415763

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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