Article

Multimodal hierarchical classification of CITE-seq data delineates immune cell states across lineages and tissues

2023-07-07

Abstract excerpt

<h4>ABSTRACT</h4> Single-cell RNA sequencing (scRNA-seq) is invaluable for profiling cellular heterogeneity and dissecting transcriptional states, but transcriptomic profiles do not always delineate subsets defined by surface proteins, as in cells of the immune system. Cellular Indexing of Transcriptomes and Epitopes (CITE-seq) enables simultaneous profiling of single-cell transcriptomes and surface proteomes; ho...

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Literature Corpus work: a1672b46-7e79-52bd-b6a0-c117a2711604
DOI: 10.1101/2023.07.06.547944

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