Article
A Human Tissue-Specific Transcriptomic Analysis Reveals that Ageing Hinders Cancer and Boosts Cellular Senescence
2019-03-31
Abstract excerpt
Ageing is the biggest risk factor for cancer, but the mechanisms linking these two processes remain unclear. We compared genes differentially expressed with age and genes differentially expressed in cancer among nine human tissues. In most tissues, ageing and cancer gene expression surprisingly changed in the opposite direction. These overlapping gene sets were related to several processes, mainly cell cycle and t...
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Identifiers and source
- Literature Corpus work
- a1645d8b-8953-50a8-9106-03b27abfba90
- DOI
- 10.1101/595041